Research

Our research and development efforts are focused on the identification and qualification of new pipeline opportunities. We apply our proprietary HGMS technology platform to these areas of unmet clinical need to develop ancillary diagnostic and prognostic tests.

We are expanding our research and development pipeline and are actively seeking new collaborative research partnerships with principal investigators and key opinion leaders.

Technology Platform Icon

Technology Platform

Our technology platform is well suited to address clinically challenging problems for which collaborative research partners can provide us with one of the following types of specimens:

  • Formalin fixed paraffin embedded (FFPE) tissue
  • Biofluids that are directly relevant to the focus disease or condition
  • Cytologic material
  • Other biological specimens
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Collaborative Research Icon

Collaborative Research

We are focused on collaborative research and development projects with the potential to result in ancillary diagnostic and prognostic tests that improve a physician's ability to:

  • Diagnose disease
  • Identify disease stage or grade
  • Predict disease response to treatment
  • Predict disease progression
  • Predict disease recurrence

A new project is typically initiated with a discussion about our technology and how it might address an unmet clinical need. While this initial discussion can generally be accomplished via teleconference or webinar, we are willing to arrange a time for a New River Labs representative to visit your institution, present our capabilities, and answer any questions that you or your team may have.

Once a project has been mutually agreed upon, the collaborative research process generally involves the following three phases:

1

Pilot Study

The first step is to conduct a pilot study to determine if molecular differences can be detected between phenotypes. Typically, about 25 specimens per phenotype are used in this phase of the project, allowing us to achieve statistical confidence in the results.

2

Expanded Study

If the results from the pilot study look promising, the project is then expanded to provide a sufficient number of specimens to generate a classification algorithm (training set) and to evaluate its accuracy in an independent set of specimens (validation set). The number of specimens necessary for this phase will depend on the complexity of the test being developed, but generally, this phase requires a couple hundred specimens.

3

Method Validation

Finally, an additional, smaller set of specimens will be needed to perform method validation to meet the requirements under CLIA related to the performance of high complexity clinical laboratory testing. Upon successful completion of this phase, we will be able to offer our test to relevant physicians.

Our collaborative research partners are highly involved in all aspects of test development and validation.

In addition, they help us increase awareness of the test, by means of scientific presentations and publications, within the relevant physician community.

Please email research@newriverlabs.com if you have an idea that you would like to discuss with a member of our research and development team.

New River Labs Clinical Research Partners