In the 1990s and early 2000s, genomic research advanced considerably as a result of the Human Genome Project. During this period of genomic research progress, proteomic research efforts began to emerge, and over the next decade, we witnessed a comparable increase in our scientific understanding of the proteome and posttranslational modifications (PTMs) as well as their roles in various diseases.
These trends in basic research have also been observed in the advancement of molecular profiling tests. Objective results have supplanted subjective results. Molecular insight has expanded dramatically due to machine learning classification algorithms. And gene focused tests are now transitioning to proteomic and metabolomic focused tests that provide a broader molecular snapshot of a patient’s tumor along with the phenotypic information that is critical to delivering on the promise of precision medicine.
In order to provide a broader context for the histology guided mass spectrometry (HGMS) profiling technology that we employ in our molecular profiling tests, we have published an online whitepaper, “The Evolution of Molecular Profiling Tests and Their Roles in Precision Medicine and Oncology.” In this whitepaper, we discuss the following topics:
- What is Precision Medicine?
- How Does Precision Medicine Impact Oncology?
- What are the Roles of Molecular Profiling Tests?
- Early Molecular Profiling Tests
- Current Molecular Profiling Tests
- Emerging Molecular Profiling Tests
As we address each of the molecular profiling technologies, we provide a brief description as well as a discussion of the technology’s benefits and limitations. In addition, we have included numerous third-party references throughout the whitepaper to afford the reader a more detailed perspective on the corresponding topic.
Please feel free to read the whitepaper online, download for offline review, and/or share it with others. If you have questions about the whitepaper content, our technology, or our tests, please email us at firstname.lastname@example.org or call us at (800) 850-5675.